RFA-NS-18-046 Analytical and/or Clinical Validation of a Candidate Biomarker for Pain (R61/R33 Clinical Trial Optional) . The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the validation of strong candidate biomarkers and endpoints for pain that can be used to facilitate the development of non-opioid pain therapeutics from discovery through Phase II clinical Analytical and Clinical Validation of a Candidate PAR-18-664 Clinical Validation of a Candidate Biomarker for Neurological Disease (U01 Clinical Trial Optional) The purpose of this Funding Opportunity Announcement (FOA) is to support rigorous clinical validation of a candidate biomarker using retrospective and/or prospective methods in a manner that is consistent with the purpose of the biomarker. RFA-NS-18-041: Discovery of Biomarkers, Biomarker New Funding Opportunity announcement released under the NIH Helping to end Addiction Long-Term (HEAL) Initiative: an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis. Access the RFA here. Also, please continue to visit the NIH Pain Consortium for HEAL Initiative for updates. New Funding Available for Basic and Mechanistic Research
Jun 01, 2017 · A biomarker (short for biological marker) is an objective measure that captures what is happening in a cell or an organism at a given moment. Biomarkers help us understand relationships between environmental chemicals and human diseases to improve our ability to diagnose, monitor, or predict disease risk.
Discovery of Biomarkers, Biomarker Signatures, and RFA-NS-18-041 The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery of strong candidate biomarkers and endpoints for pain that can be used to facilitate the development of non-opioid pain therapeutics from discovery through Phase II clinical trials. Specifically, the focus of this FOA is on the identification and initial biological, analytical and Biomarkers in Children with Chronic Abdominal Pain Biomarkers in Children with Chronic Abdominal Pain There are molecular differences beneath the surface of childhood abdominal pain and identifying them may lead to better diagnosis and novel treatments, according to a study by NINR intramural researchers.
Concepts describe the basic purpose, scope and objectives of proposed initiatives and represent an early planning stage for potential Ncats activities.
Webinar: Developing Biomarkers for Neurological Disorders Oct 30, 2018 · The NIH HEAL Biomarker initiative is intended to promote the discovery and validation of strong candidate biomarkers and endpoints for pain that can be used to facilitate the development of non-addictive pain therapeutics. Acute to Chronic Pain Signatures | NIH Common Fund Jan 12, 2020 · The goal of the Acute to Chronic Pain Signatures (A2CPS) program is to develop a set of objective biomarkers that provide “signatures” to predict if chronic pain is likely to develop after acute pain. Such signatures are greatly needed as prevention of chronic pain after an acute pain event is a major challenge in pain management. Clinical Research in Pain Management | NIH HEAL Initiative
11 Apr 2019 In November 2018, the NIH held a two-day workshop in Washington, DC, to discuss the current state and future outlook for the development of biomarkers for pain and pain treatment response. The meeting was co-chaired by
Advancing clinical research on pain management is a core goal of the Helping to End Addiction Long-term SM Initiative, or NIH HEAL Initiative SM.The NIH HEAL Initiative will support both new clinical trial programs and the expansion of existing programs to evaluate the safety and efficacy of innovative therapies for pain management. RFA-NS-18-041: Discovery of Biomarkers, Biomarker NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain …